Is Long-Term Melatonin Use Safe? New Study Raises Concerns for Heart Health

Melatonin is often the first thing many people think of when they cannot sleep. It is easy to find, affordable, and commonly believed to be gentle on the body. But new research suggests that long-term melatonin use may not be as harmless as previously thought. The study has drawn attention because it points to possible risks for heart health among people who use melatonin regularly over a long period.

Why Do People Take Melatonin?

Melatonin is a hormone that our brain naturally releases to help signal bedtime. However, due to stress, late-night screen time, or irregular routines, some people struggle to fall asleep. To solve this, many turn to synthetic melatonin. In many countries, melatonin supplements can be bought without a prescription, which makes it even more common.

Because of this easy access, some people end up using melatonin every night, sometimes without medical guidance.

What the New Research Found

The study reviewed data from more than 130,000 adults who had chronic insomnia. The participants were divided into two groups: those who had taken melatonin for at least one year and those who had never used it.

The results were surprising:

  • People who used melatonin long-term had a higher risk of developing heart failure.
  • They were also more likely to be hospitalized due to heart failure symptoms.
  • The study also found a higher risk of death among long-term melatonin users over a five-year period.

The researchers made it clear that this does not prove melatonin directly causes these outcomes. However, the consistent trend suggests the need for more understanding and caution.

Comparison Between Users and Non-Users

Health Outcome (Over 5 Years)Long-Term Melatonin UsersNon-Users
Risk of Heart FailureHigherLower
Hospitalization for Heart FailureMuch HigherLower
Risk of DeathHigherLower

This comparison shows why the findings are gaining attention.

What Should People Do?

This does not mean melatonin is unsafe for everyone. Short-term use, like adjusting to a new sleep schedule or recovering from travel, may still be helpful. The concern is daily, long-term use without medical direction.

Instead of relying on supplements every night, try building healthier sleep habits:

  • Go to bed and wake up at the same time every day
  • Keep the bedroom dark and quiet
  • Limit caffeine and heavy meals late in the day
  • Reduce screen exposure before bedtime

If insomnia continues, it may help to speak with a doctor or sleep specialist to explore safe, long-lasting solutions.

Final Thoughts

The study suggests that long-term melatonin use may carry risks that many people do not know about. While the research is still developing, it serves as a reminder that even “natural” supplements should be used thoughtfully. Before continuing long-term nightly melatonin, consider discussing your sleep routine with a healthcare professional to protect both your rest and your heart health.

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